NUPACK is a software suite for the design and analysis of DNA strands and multi-strand complexes1. NUPACK can be used to predict an oligo's secondary structure, as well as the complementary interactions between arbitrary numbers of nucleotides.
References
- Fornace, M. E. et al. NUPACK: Computational Nucleic Acid Analysis and Design. ACS Synth. Biol. 15, 1426–1441 (2026).